Molecular, cellular and medical aspects of the action of nutraceuticals and small molecules therapeutics: from chemoprevention to new drug development
by
Colic M, Pavelic K.
Molecutec Corporation,
Goleta, California, USA.
Am J Clin Nutr. 2003 Apr;77(4 Suppl):1001S-1007S


ABSTRACT

Dietary supplements, functional foods and their concentrated, sometimes purified, active forms, the so-called nutraceuticals, are becoming increasingly popular throughout the world. Small molecules that regulate signal transduction cascades and gene expression are being tested by many pharmaceutical companies. A rapidly and exponentially growing industry (close to $30 billion in 1999 worldwide) exists to commercialize and exploit this interest. However, the scientific basis of the action of such unproved products is in the very early stages of development. While supporters claim they produce miracle cures, opponents argue that such unproved agents do more harm than good.
Folate
Inositol
Serotonin
Chromium
Tryptophan
Low-fat blues
Nutrigenomics
Iron deficiency
Functional foods
Food and cancer
Nutraceuticals/functional foods
Functional foods as slimming aids


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